PDBe 3uqo

X-ray diffraction
1.8Å resolution

Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cationic trypsin Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.41 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P3221
Unit cell:
a: 54.692Å b: 54.692Å c: 112.953Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.2 0.256
Expression system: Escherichia coli BL21(DE3)