3uk6

X-ray diffraction
2.95Å resolution

Crystal Structure of the Tip48 (Tip49b) hexamer

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RuvB-like 2 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 368 amino acids
Theoretical weight: 40.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y230 (Residues: 1-132, 239-463; Coverage: 77%)
Gene names: CGI-46, INO80J, RUVBL2, TIP48, TIP49B
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 113.07Å b: 186.28Å c: 129.86Å
α: 90° β: 108.95° γ: 90°
R-values:
R R work R free
0.242 0.241 0.264
Expression system: Escherichia coli BL21(DE3)