PDBe 3tsb

X-ray diffraction
2.6Å resolution

Function and Biology Details

Reaction catalysed:
Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inosine-5'-monophosphate dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 511 amino acids
Theoretical weight: 55.18 KDa
Source organism: Bacillus anthracis str. Ames
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q81W29 (Residues: 1-487; Coverage: 100%)
Gene names: GBAA_0008, guaB
Sequence domains:
Structure domains: Aldolase class I

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I4
Unit cell:
a: 123.026Å b: 123.026Å c: 140.718Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.242
Expression system: Escherichia coli BL21