3tqc

X-ray diffraction
2.3Å resolution

Structure of the pantothenate kinase (coaA) from Coxiella burnetii

Released:

Function and Biology Details

Reaction catalysed:
ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pantothenate kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 321 amino acids
Theoretical weight: 37.24 KDa
Source organism: Coxiella burnetii
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q83EV9 (Residues: 1-318; Coverage: 100%)
Gene names: CBU_0199, coaA
Sequence domains: Phosphoribulokinase / Uridine kinase family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4C
Spacegroup: P21
Unit cell:
a: 63.214Å b: 94.698Å c: 75.398Å
α: 90° β: 106.4° γ: 90°
R-values:
R R work R free
0.214 0.211 0.269
Expression system: Escherichia coli BL21(DE3)