3tlx

X-ray diffraction
2.75Å resolution

Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum

Released:
Source organism: Plasmodium falciparum
Entry authors: Wernimont AK, Loppnau P, Crombet L, Weadge J, Perieteanu A, Edwards AM, Arrowsmith CH, Park H, Bountra C, Hui R, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed:
ATP + AMP = 2 ADP
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADK_lid domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 243 amino acids
Theoretical weight: 27.71 KDa
Source organism: Plasmodium falciparum
UniProt:
  • Canonical: Q7Z0H0 (Residues: 1-242; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 81.395Å b: 76.663Å c: 93.768Å
α: 90° β: 100.78° γ: 90°
R-values:
R R work R free
0.227 0.226 0.26