PDBe 3t3l

X-ray diffraction
1.15Å resolution

1.15 A structure of human frataxin variant Q153A

Released:

Function and Biology Details

Reaction catalysed:
4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Frataxin mature form Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16595 (Residues: 82-210; Coverage: 61%)
Gene names: FRDA, FXN, X25
Sequence domains: Frataxin-like domain
Structure domains: Frataxin/CyaY

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 87.44Å b: 32.46Å c: 45.17Å
α: 90° β: 91.87° γ: 90°
R-values:
R R work R free
0.167 0.166 0.179
Expression system: Escherichia coli