PDBe 3t1p

X-ray diffraction
3.9Å resolution

Crystal structure of an alpha-1-antitrypsin trimer


Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Alpha-1-antitrypsin Chain: A
Molecule details ›
Chain: A
Length: 371 amino acids
Theoretical weight: 41.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P01009 (Residues: 48-418; Coverage: 94%)
  • Best match: P01009-3 (Residues: 48-306)
Gene names: AAT, PI, PRO0684, PRO2209, SERPINA1
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P4132
Unit cell:
a: 163.691Å b: 163.691Å c: 163.691Å
α: 90° β: 90° γ: 90°
R R work R free
0.238 0.231 0.297
Expression system: Escherichia coli