X-ray diffraction
1.95Å resolution

Crystal structure of ca2+-calmodulin in complex with a trpv1 c-terminal peptide


Function and Biology Details

Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 16.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P0DP23 (Residues: 1-149; Coverage: 100%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair
Transient receptor potential cation channel subfamily V member 1 Chain: B
Molecule details ›
Chain: B
Length: 37 amino acids
Theoretical weight: 4.08 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: O35433 (Residues: 767-801; Coverage: 4%)
Gene names: Trpv1, Vr1, Vr1l

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P6122
Unit cell:
a: 41.681Å b: 41.681Å c: 341.533Å
α: 90° β: 90° γ: 120°
R R work R free
0.194 0.192 0.248
Expression system: Escherichia coli BL21(DE3)