3sov

X-ray diffraction
1.27Å resolution

The structure of a beta propeller domain in complex with peptide S

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Low-density lipoprotein receptor-related protein 6 Chain: A
Molecule details ›
Chain: A
Length: 318 amino acids
Theoretical weight: 35.69 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O75581 (Residues: 20-326; Coverage: 19%)
Gene name: LRP6
Sequence domains:
Structure domains:
Sclerostin Chain: Z
Molecule details ›
Chain: Z
Length: 9 amino acids
Theoretical weight: 765 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9BQB4 (Residues: 115-121; Coverage: 4%)
Gene names: SOST, UNQ2976/PRO7455/PRO7476

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 103.567Å b: 47.09Å c: 68.72Å
α: 90° β: 97.68° γ: 90°
R-values:
R R work R free
0.154 0.153 0.18
Expression systems:
  • Spodoptera frugiperda
  • Not provided