› 3snh

X-ray diffraction
3.7Å resolution

Crystal structure of nucleotide-free human dynamin1

Released:
DOI: 10.2210/pdb3snh/pdb
PDB entry 3snh coloured by chain, front view.
PDB entry 3snh coloured by chain, side view.
PDB entry 3snh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of nucleotide-free dynamin.
Faelber K, Posor Y, Gao S, Held M, Roske Y, Schulze D, Haucke V, Noé F, Daumke O
Nature 477 556-60 (2011)
PMID: 21927000

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170158 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynamin-1 Chain: A
Molecule details ›
Chain: A
Length: 743 amino acids
Theoretical weight: 85.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05193 (Residues: 6-746; Coverage: 86%)
Gene names: DNM, DNM1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C2221
Unit cell:
a: 155.056Å b: 201.993Å c: 59.016Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.29 0.288 0.33
Expression system: Escherichia coli

Quick links

Citations

54 review citations

Mitochondrial form and function.
Friedman et al. (2014)
53 more

32 mentions without citation

Dynamin, a membrane-remodelling GTPase.
Ferguson et al. (2012)
31 more