3rvv

X-ray diffraction
1.9Å resolution

Crystal structure of Der f 1 complexed with Fab 4C1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Peptidase 1 Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 25.22 KDa
Source organism: Dermatophagoides farinae
UniProt:
  • Canonical: P16311 (Residues: 99-321; Coverage: 74%)
Gene name: DERF1
Sequence domains: Papain family cysteine protease
Structure domains: Cysteine proteinases
4C1 - light chain Chain: C
Molecule details ›
Chain: C
Length: 213 amino acids
Theoretical weight: 23.94 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins
4C1 - heavy chain Chain: D
Molecule details ›
Chain: D
Length: 255 amino acids
Theoretical weight: 27.68 KDa
Source organism: Mus musculus
Expression system: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P21
Unit cell:
a: 65.403Å b: 79.428Å c: 72.199Å
α: 90° β: 105.2° γ: 90°
R-values:
R R work R free
0.153 0.15 0.196
Expression system: Mus musculus