X-ray diffraction
1.1Å resolution

crystal structure of LGN/mInscuteable complex


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
G-protein-signaling modulator 2 Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 18.37 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: Q8VDU0 (Residues: 198-357; Coverage: 24%)
Gene names: Gpsm2, Lgn, Pins
Sequence domains:
Structure domains: Tetratricopeptide repeat domain
Protein inscuteable homolog Chain: B
Molecule details ›
Chain: B
Length: 22 amino acids
Theoretical weight: 2.8 KDa
Source organism: Mus musculus
Expression system: Not provided
  • Canonical: Q3HNM7 (Residues: 66-87; Coverage: 4%)
Gene name: Insc

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 88.196Å b: 75.606Å c: 35.346Å
α: 90° β: 105.99° γ: 90°
R R work R free
0.12 not available 0.15
Expression systems:
  • Escherichia coli
  • Not provided