PDBe 3rcp

X-ray diffraction
1.9Å resolution

Crystal structure of the FAPP1 pleckstrin homology domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pleckstrin homology domain-containing family A member 3 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9HB20 (Residues: 1-99; Coverage: 33%)
Gene names: FAPP1, PLEKHA3
Sequence domains: PH domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P41212
Unit cell:
a: 31.025Å b: 31.025Å c: 216.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.265 0.23 0.255
Expression system: Escherichia coli BL21(DE3)