3rco

X-ray diffraction
1.8Å resolution

Crystal structure of a conserved motif in human TDRD7

Released:
Source organism: Homo sapiens
Entry authors: Dong A, Xu C, Walker JR, Lam R, Guo Y, Bian C, Li Y, Bountra C, Weigelt J, Arrowsmith CH, Edwards AM, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo 24-mer
homo dodecamer
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tudor domain-containing protein 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 89 amino acids
Theoretical weight: 9.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8NHU6 (Residues: 1-82; Coverage: 8%)
Gene names: PCTAIRE2BP, TDRD7
Sequence domains: OST-HTH/LOTUS domain
Structure domains: LOTUS domain-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I23
Unit cell:
a: 99.788Å b: 99.788Å c: 99.788Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.174 0.23
Expression system: Escherichia coli BL21(DE3)