X-ray diffraction
2.35Å resolution

Crystal structure of a TetR-family transcriptional regulator (HI0893) from Haemophilus influenzae RD at 2.35 A resolution

Source organism: Haemophilus influenzae
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Uncharacterized HTH-type transcriptional regulator HI_0893 Chains: A, B
Molecule details ›
Chains: A, B
Length: 188 amino acids
Theoretical weight: 22.39 KDa
Source organism: Haemophilus influenzae
Expression system: Escherichia coli
  • Canonical: P44923 (Residues: 1-187; Coverage: 100%)
Gene name: HI_0893
Sequence domains: Bacterial regulatory proteins, tetR family
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P62
Unit cell:
a: 71.16Å b: 71.16Å c: 159.334Å
α: 90° β: 90° γ: 120°
R R work R free
0.224 0.223 0.248
Expression system: Escherichia coli