› 3qcw

X-ray diffraction
2.65Å resolution

Structure of neurexin 1 alpha (domains LNS1-LNS6), no splice inserts

Released:
DOI: 10.2210/pdb3qcw/pdb
PDB 3qcw coloured by chain and viewed from the front.
PDB 3qcw coloured by chain and viewed from the side.
PDB 3qcw coloured by chain and viewed from the top.
Source organism: Bos taurus
Primary publication:
The structure of neurexin 1α reveals features promoting a role as synaptic organizer.
Chen F, Venugopal V, Murray B, Rudenko G
Structure 19 779-89 (2011)
PMID: 21620716

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Neurexin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1245 amino acids
Theoretical weight: 137.47 KDa
Source organism: Bos taurus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q28146 (Residues: 31-1359; Coverage: 83%)
  • Best match: Q28146-6 (Residues: 31-1333)
Gene name: NRXN1
Sequence domains: Laminin G domain
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P1
Unit cell:
a: 60.953Å b: 114.543Å c: 159.581Å
α: 90.61° β: 90.87° γ: 92.18°
R-values:
R R work R free
0.209 0.208 0.23
Expression system: Spodoptera frugiperda

Quick links

Citations

10 review citations

Neurexins: molecular codes for shaping neuronal synapses.
Gomez et al. (2021)
9 more

8 mentions without citation

Latrophilin's Social Protein Network.
Burbach et al. (2019)
7 more