PDBe 3pyh

X-ray diffraction
2Å resolution

Bovine trypsin variant X(tripleGlu217Ile227) in complex with small molecule inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cationic trypsin Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.42 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P65
Unit cell:
a: 81.679Å b: 81.679Å c: 63.521Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.159 0.157 0.218
Expression system: Escherichia coli