› 3pwv

X-ray diffraction
2.7Å resolution

An immmunodominant CTL epitope from rinderpest virus presented by cattle MHC class I molecule N*01801 (BoLA-A11)

Released:
DOI: 10.2210/pdb3pwv/pdb
PDB entry 3pwv coloured by chain, front view.
PDB entry 3pwv coloured by chain, side view.
PDB entry 3pwv coloured by chain, top view.
Source organisms:
Primary publication:
Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides.
Li X, Liu J, Qi J, Gao F, Li Q, Li X, Zhang N, Xia C, Gao GF
J Virol 85 6038-48 (2011)
PMID: 21450819

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135127 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Ig-like domain-containing protein Chains: A, D
Molecule details ›
Chains: A, D
Length: 274 amino acids
Theoretical weight: 31.8 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q95477 (Residues: 26-299; Coverage: 81%)
Gene name: LA-A11
Sequence domains:
Structure domains:
Beta-2-microglobulin Chains: B, E
Molecule details ›
Chains: B, E
Length: 98 amino acids
Theoretical weight: 11.65 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01888 (Residues: 21-118; Coverage: 100%)
Gene name: B2M
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Hemagglutinin glycoprotein Chains: C, F
Molecule details ›
Chains: C, F
Length: 9 amino acids
Theoretical weight: 946 Da
Source organism: Rinderpest morbillivirus
Expression system: Not provided
UniProt:
  • Canonical: Q9YKD7 (Residues: 407-415; Coverage: 2%)
Gene name: HA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P41
Unit cell:
a: 83.905Å b: 83.905Å c: 153.005Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.232
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

1 review citation

New vistas unfold: Chicken MHC molecules reveal unexpected ways to present peptides to the immune system.
Halabi et al. (2022)
27 other articles

5 mentions without citation

Two distinct conformations of a rinderpest virus epitope presented by bovine major histocompatibility complex class I N*01801: a host strategy to present featured peptides.
Li et al. (2011)
4 more