3pim

X-ray diffraction
1.9Å resolution

Crystal structure of Mxr1 from Saccharomyces cerevisiae in unusual oxidized form

Released:

Function and Biology Details

Reaction catalysed:
L-methionine + thioredoxin disulfide + H(2)O = L-methionine (S)-S-oxide + thioredoxin
Biochemical function:
Cellular component:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptide methionine sulfoxide reductase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 187 amino acids
Theoretical weight: 21.51 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P40029 (Residues: 2-184; Coverage: 100%)
Gene names: MXR1, YER042W
Sequence domains: Peptide methionine sulfoxide reductase
Structure domains: Peptide methionine sulphoxide reductase MsrA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P3121
Unit cell:
a: 111.894Å b: 111.894Å c: 108.124Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.238 0.236 0.264
Expression system: Escherichia coli