X-ray diffraction
1.06Å resolution

Human adipocyte lipid-binding protein FABP4 in complex with 3-(4-methoxy-3-methylphenyl) propionic acid

Source organism: Homo sapiens
Primary publication:
Structural analysis of ibuprofen binding to human adipocyte fatty-acid binding protein (FABP4).
Acta Crystallogr F Struct Biol Commun 71 163-70 (2015)
PMID: 25664790

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Fatty acid-binding protein, adipocyte Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P15090 (Residues: 1-132; Coverage: 100%)
Gene name: FABP4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P212121
Unit cell:
a: 32.244Å b: 53.392Å c: 75.015Å
α: 90° β: 90° γ: 90°
R R work R free
0.141 0.14 0.161
Expression system: Escherichia coli