3oes

X-ray diffraction
2.3Å resolution

Crystal structure of the small GTPase RhebL1

Released:
Source organism: Homo sapiens
Entry authors: Nedyalkova L, Zhong N, Tempel W, Tong Y, Shen L, Loppnau P, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTPase RhebL1 Chain: A
Molecule details ›
Chain: A
Length: 201 amino acids
Theoretical weight: 22.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TAI7 (Residues: 1-183; Coverage: 100%)
Gene name: RHEBL1
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2221
Unit cell:
a: 72.665Å b: 126.745Å c: 41.356Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.212 0.271
Expression system: Escherichia coli