3o71

X-ray diffraction
1.95Å resolution

Crystal structure of ERK2/DCC peptide complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mitogen-activated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 358 amino acids
Theoretical weight: 41.33 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P63086 (Residues: 1-358; Coverage: 100%)
Gene names: Erk2, Mapk, Mapk1, Prkm1
Sequence domains: Protein kinase domain
Structure domains:
Netrin receptor DCC Chain: B
Molecule details ›
Chain: B
Length: 27 amino acids
Theoretical weight: 3.35 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: Q63155 (Residues: 1140-1166; Coverage: 2%)
Gene name: Dcc

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P321
Unit cell:
a: 87.178Å b: 87.178Å c: 94.459Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.199 0.24
Expression systems:
  • Escherichia coli
  • Not provided