3nxb

X-ray diffraction
1.83Å resolution

Crystal Structure of the Bromodomain of human CECR2

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cat eye syndrome critical region protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 116 amino acids
Theoretical weight: 13.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BXF3 (Residues: 424-538; Coverage: 8%)
Gene names: CECR2, KIAA1740
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: C2
Unit cell:
a: 127.16Å b: 45.51Å c: 45.59Å
α: 90° β: 105.67° γ: 90°
R-values:
R R work R free
0.178 0.176 0.214
Expression system: Escherichia coli BL21(DE3)