X-ray diffraction
2.6Å resolution

Crystal Structure of Bovine Xanthine Oxidase in Complex with 6-Mercaptopurine


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Xanthine dehydrogenase/oxidase Chains: A, J
Molecule details ›
Chains: A, J
Length: 164 amino acids
Theoretical weight: 18 KDa
Source organism: Bos taurus
  • Canonical: P80457 (Residues: 2-165; Coverage: 12%)
Gene name: XDH
Sequence domains:
Structure domains:
Xanthine dehydrogenase/oxidase Chains: B, K
Xanthine dehydrogenase/oxidase Chains: C, L

Ligands and Environments

Cofactor: Ligand MTE 2 x MTE

Cofactor: Ligand FAD 2 x FAD
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 134.636Å b: 73.928Å c: 140.353Å
α: 90° β: 97.01° γ: 90°
R R work R free
0.22 0.217 0.269