3nrz

X-ray diffraction
1.8Å resolution

Crystal Structure of Bovine Xanthine Oxidase in Complex with Hypoxanthine

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
Non-polymer only hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Xanthine dehydrogenase/oxidase Chains: A, J
Molecule details ›
Chains: A, J
Length: 164 amino acids
Theoretical weight: 18 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P80457 (Residues: 2-165; Coverage: 12%)
Gene name: XDH
Sequence domains:
Structure domains:
Xanthine dehydrogenase/oxidase Chains: B, K
Xanthine dehydrogenase/oxidase Chains: C, L
Molecule details ›
Chains: C, L
Length: 756 amino acids
Theoretical weight: 83.1 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P80457 (Residues: 571-1326; Coverage: 57%)
Gene name: XDH
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 2 x FAD

Cofactor: Ligand MTE 2 x MTE
3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 133.016Å b: 73.645Å c: 138.696Å
α: 90° β: 97.05° γ: 90°
R-values:
R R work R free
0.199 0.197 0.234