3ney

X-ray diffraction
2.26Å resolution

Crystal structure of the kinase domain of MPP1/p55

Released:
Source organism: Homo sapiens
Entry authors: Shen Y, Tong Y, Zhong N, Guan X, Tempel W, MacKenzie F, Arrowsmith CH, Edwards AM, Bountra C, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
55 kDa erythrocyte membrane protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 197 amino acids
Theoretical weight: 22.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q00013 (Residues: 282-460; Coverage: 38%)
Gene names: DXS552E, EMP55, MPP1
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P212121
Unit cell:
a: 72.088Å b: 131.562Å c: 237.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.235 0.271
Expression system: Escherichia coli BL21