PDBe 3nbh

X-ray diffraction
2Å resolution

Crystal structure of human RMI1C-RMI2 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RecQ-mediated genome instability protein 1 Chain: A
Molecule details ›
Chain: A
Length: 155 amino acids
Theoretical weight: 17.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H9A7 (Residues: 475-625; Coverage: 24%)
Gene names: C9orf76, RMI1
Sequence domains: Recq-mediated genome instability protein 1, C-terminal OB-fold
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
RecQ-mediated genome instability protein 2 Chain: B
Molecule details ›
Chain: B
Length: 147 amino acids
Theoretical weight: 16.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96E14 (Residues: 6-147; Coverage: 97%)
Gene names: C16orf75, RMI2
Sequence domains: RecQ-mediated genome instability protein 2
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P212121
Unit cell:
a: 41.682Å b: 42.365Å c: 157.734Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.258
Expression system: Escherichia coli BL21(DE3)