X-ray diffraction
2.53Å resolution

Crystal structure of Helicobactor pylori shikimate kinase in complex with NSC162535


Function and Biology Details

Reaction catalysed:
ATP + shikimate = ADP + shikimate 3-phosphate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Shikimate kinase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 168 amino acids
Theoretical weight: 19 KDa
Source organism: Helicobacter pylori 26695
Expression system: Escherichia coli
  • Canonical: P56073 (Residues: 1-162; Coverage: 100%)
Gene names: HP_0157, aroK
Sequence domains: Shikimate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL12B2
Spacegroup: C2
Unit cell:
a: 193.91Å b: 71.791Å c: 47.626Å
α: 90° β: 91.96° γ: 90°
R R work R free
0.219 0.217 0.263
Expression system: Escherichia coli