PDBe 3mxn

X-ray diffraction
1.55Å resolution

Crystal structure of the RMI core complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RecQ-mediated genome instability protein 1 Chain: A
Molecule details ›
Chain: A
Length: 157 amino acids
Theoretical weight: 17.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H9A7 (Residues: 473-625; Coverage: 25%)
Gene names: C9orf76, RMI1
Sequence domains: Recq-mediated genome instability protein 1, C-terminal OB-fold
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
RecQ-mediated genome instability protein 2 Chain: B
Molecule details ›
Chain: B
Length: 150 amino acids
Theoretical weight: 16.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96E14 (Residues: 1-147; Coverage: 100%)
Gene names: C16orf75, RMI2
Sequence domains: RecQ-mediated genome instability protein 2
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P212121
Unit cell:
a: 42.096Å b: 42.223Å c: 152.24Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.231
Expression system: Escherichia coli