3m1c

X-ray diffraction
3Å resolution

Crystal structure of the conserved herpesvirus fusion regulator complex gH-gL

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Envelope glycoprotein H Chain: A
Molecule details ›
Chain: A
Length: 762 amino acids
Theoretical weight: 81.63 KDa
Source organism: Human herpesvirus 2 strain HG52
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P89445 (Residues: 48-803; Coverage: 92%)
Gene names: UL22, gH
Structure domains:
Envelope glycoprotein L Chain: B
Molecule details ›
Chain: B
Length: 204 amino acids
Theoretical weight: 23.19 KDa
Source organism: Human herpesvirus 2 strain HG52
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P28278 (Residues: 21-224; Coverage: 98%)
Gene names: UL1, gL
Sequence domains: Herpesvirus glycoprotein L
Structure domains: Enolase-like; domain 1

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41212
Unit cell:
a: 88.255Å b: 88.255Å c: 333.406Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.17 0.242
Expression system: Spodoptera frugiperda