3ld8

X-ray diffraction
2.7Å resolution

Structure of JMJD6 and Fab Fragments

Released:
Primary publication:
Interaction of JMJD6 with single-stranded RNA.
Proc. Natl. Acad. Sci. U.S.A. 107 14568-72 (2010)
PMID: 20679243

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 Chain: A
Molecule details ›
Chain: A
Length: 334 amino acids
Theoretical weight: 39.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6NYC1 (Residues: 1-334; Coverage: 83%)
Gene names: JMJD6, KIAA0585, PSR, PTDSR
Sequence domains: JmjC domain, hydroxylase
Structure domains:
antibody Fab fragment light chain Chain: B
Molecule details ›
Chain: B
Length: 220 amino acids
Theoretical weight: 24.1 KDa
Source organism: Cricetulus migratorius
Expression system: Cricetulus migratorius
Structure domains: Immunoglobulins
antibody Fab fragment heavy chain Chain: C
Molecule details ›
Chain: C
Length: 221 amino acids
Theoretical weight: 24.01 KDa
Source organism: Cricetulus migratorius
Expression system: Cricetulus migratorius
Structure domains: Immunoglobulins

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1, ALS BEAMLINE 8.2.2
Spacegroup: P41212
Unit cell:
a: 138.281Å b: 138.281Å c: 183.554Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 0.26
Expression systems:
  • Escherichia coli
  • Cricetulus migratorius