PDBe 3l6j

X-ray diffraction
2.3Å resolution

Structure of cinaciguat (bay 58-2667) bound to nostoc H-NOX domain

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo hexamer
homo dimer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alr2278 protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 189 amino acids
Theoretical weight: 21.21 KDa
Source organism: Nostoc sp. PCC 7120
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8YUQ7 (Residues: 1-189; Coverage: 100%)
Gene name: alr2278
Sequence domains: Haem-NO-binding
Structure domains: H-NOX domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P213
Unit cell:
a: 123.268Å b: 123.268Å c: 123.268Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.153 0.15 0.193
Expression system: Escherichia coli