X-ray diffraction
2.1Å resolution

Crystal structure of the master transcriptional regulator, SmcR, in Vibrio vulnificus provides insight into its DNA recognition mechanism


Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
HTH tetR-type domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 206 amino acids
Theoretical weight: 24.05 KDa
Source organism: Vibrio vulnificus
Expression system: Escherichia coli
  • Canonical: Q9L8G8 (Residues: 1-205; Coverage: 100%)
Gene names: CRN35_14615, CRN52_17705, D8T54_02235, D8T65_23975, FORC53_0519, JS86_16400, XM75_c12331, smcR, vvpR
Sequence domains: Bacterial regulatory proteins, tetR family
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 6C1
Spacegroup: P212121
Unit cell:
a: 78.494Å b: 99.025Å c: 129.06Å
α: 90° β: 90° γ: 90°
R R work R free
0.212 0.198 0.251
Expression system: Escherichia coli