3kut

X-ray diffraction
1.5Å resolution

Crystal structure of the MLLE domain of poly(A)-binding protein in complex with the binding region of Paip2

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polyadenylate-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 88 amino acids
Theoretical weight: 9.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11940 (Residues: 544-626; Coverage: 13%)
Gene names: PAB1, PABP1, PABPC1, PABPC2
Sequence domains: Poly-adenylate binding protein, unique domain
Structure domains: c-terminal domain of poly(a) binding protein
Polyadenylate-binding protein-interacting protein 2 Chains: C, D
Molecule details ›
Chains: C, D
Length: 17 amino acids
Theoretical weight: 1.78 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9BPZ3 (Residues: 109-125; Coverage: 13%)
Gene names: HSPC218, PAIP2, PAIP2A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P1
Unit cell:
a: 26.309Å b: 31.748Å c: 48.454Å
α: 100.29° β: 90.37° γ: 99.05°
R-values:
R R work R free
0.169 0.168 0.201
Expression systems:
  • Escherichia coli
  • Not provided