3ktr

X-ray diffraction
1.7Å resolution

Structural basis of ataxin-2 recognition by poly(A)-binding protein

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polyadenylate-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P11940 (Residues: 544-626; Coverage: 13%)
Gene names: PAB1, PABP1, PABPC1, PABPC2
Sequence domains: Poly-adenylate binding protein, unique domain
Structure domains: c-terminal domain of poly(a) binding protein
Ataxin-2 Chain: B
Molecule details ›
Chain: B
Length: 17 amino acids
Theoretical weight: 1.94 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q99700 (Residues: 912-928; Coverage: 1%)
Gene names: ATX2, ATXN2, SCA2, TNRC13

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P21212
Unit cell:
a: 39.093Å b: 60.745Å c: 31.52Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.212 0.245
Expression systems:
  • Escherichia coli
  • Not provided