X-ray diffraction
2.55Å resolution

Transposase domain of Metnase


Function and Biology Details

Reaction catalysed:
(1a) S-adenosyl-L-methionine + a [histone H3]-L-lysine(36) = S-adenosyl-L-homocysteine + a [histone H3]-N(6)-methyl-L-lysine(36)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Histone-lysine N-methyltransferase SETMAR Chains: A, B
Molecule details ›
Chains: A, B
Length: 239 amino acids
Theoretical weight: 28.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q53H47 (Residues: 446-684; Coverage: 35%)
Gene name: SETMAR
Sequence domains: Transposase (partial DDE domain)
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6122
Unit cell:
a: 82.99Å b: 82.99Å c: 289.779Å
α: 90° β: 90° γ: 120°
R R work R free
0.234 0.231 0.291
Expression system: Escherichia coli