X-ray diffraction
1.9Å resolution

Transposase domain of Metnase


Function and Biology Details

Reaction catalysed:
(1a) S-adenosyl-L-methionine + a [histone H3]-L-lysine(36) = S-adenosyl-L-homocysteine + a [histone H3]-N(6)-methyl-L-lysine(36)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Histone-lysine N-methyltransferase SETMAR Chains: A, B
Molecule details ›
Chains: A, B
Length: 239 amino acids
Theoretical weight: 28.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q53H47 (Residues: 446-684; Coverage: 35%)
Gene name: SETMAR
Sequence domains: Transposase (partial DDE domain)
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P21
Unit cell:
a: 79.158Å b: 45.411Å c: 90.678Å
α: 90° β: 113.81° γ: 90°
R R work R free
0.206 0.205 0.234
Expression system: Escherichia coli