3j0c

Electron Microscopy
4.8Å resolution

Models of E1, E2 and CP of Venezuelan Equine Encephalitis Virus TC-83 strain restrained by a near atomic resolution cryo-EM map

Released:

Function and Biology Details

Reaction catalysed:
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
hetero 720-mer (preferred)
hetero dodecamer
hetero 60-mer
hetero 72-mer
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein E1 Chains: A, D, G, J
Molecule details ›
Chains: A, D, G, J
Length: 442 amino acids
Theoretical weight: 47.95 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
UniProt:
  • Canonical: P05674 (Residues: 813-1254; Coverage: 35%)
Spike glycoprotein E2 Chains: B, E, H, K
Molecule details ›
Chains: B, E, H, K
Length: 423 amino acids
Theoretical weight: 47.11 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
UniProt:
  • Canonical: P05674 (Residues: 335-757; Coverage: 34%)
Sequence domains: Alphavirus E2 glycoprotein
Capsid protein Chains: C, F, I, L
Molecule details ›
Chains: C, F, I, L
Length: 162 amino acids
Theoretical weight: 18.2 KDa
Source organism: Venezuelan equine encephalitis virus (strain TC-83)
UniProt:
  • Canonical: P05674 (Residues: 114-275; Coverage: 13%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.8Å
Relevant EMDB volumes: EMD-5275