X-ray diffraction
1.79Å resolution

Crystal structure of the sixth bromodomain of human poly-bromodomain containing protein 1 (PB1)


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Protein polybromo-1 Chain: A
Molecule details ›
Chain: A
Length: 147 amino acids
Theoretical weight: 17.52 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q86U86 (Residues: 773-914; Coverage: 8%)
Gene names: BAF180, PB1, PBRM1
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3221
Unit cell:
a: 66.4Å b: 66.4Å c: 85.43Å
α: 90° β: 90° γ: 120°
R R work R free
0.167 0.165 0.202
Expression system: Escherichia coli