3iq2

X-ray diffraction
1.7Å resolution

Human sorting nexin 7, phox homology (PX) domain

Released:
Source organism: Homo sapiens
Entry authors: Karlberg T, Wisniewska M, Arrowsmith CH, Berglund H, Bountra C, Collins R, Edwards AM, Flodin S, Flores A, Graslund S, Hammarstrom M, Johansson A, Johansson I, Kallas A, Kotenyova T, Kotzsch A, Kraulis P, Nielsen TK, Moche M, Nordlund P, Nyman T, Persson C, Roos AK, Schutz P, Siponen MI, Thorsell AG, Tresaugues L, Van Den Berg S, Weigelt J, Welin M, Schuler H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 16.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UNH6 (Residues: 25-154; Coverage: 34%)
Gene name: SNX7
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I911-2
Spacegroup: P32
Unit cell:
a: 57.3Å b: 57.3Å c: 97.1Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.166 0.165 0.2
Expression system: Escherichia coli BL21(DE3)