3io8

X-ray diffraction
2.3Å resolution

BimL12F in complex with Bcl-xL

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bcl-2-like protein 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 158 amino acids
Theoretical weight: 17.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q07817 (Residues: 1-209; Coverage: 66%)
  • Best match: Q07817-2 (Residues: 1-125, 126-146)
Gene names: BCL2L, BCL2L1, BCLX
Sequence domains:
Bcl-2-like protein 11 Chains: B, D
Molecule details ›
Chains: B, D
Length: 26 amino acids
Theoretical weight: 3.31 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43521 (Residues: 141-166; Coverage: 13%)
Gene names: BCL2L11, BIM

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P62
Unit cell:
a: 65.717Å b: 65.717Å c: 170.094Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.185 0.231
Expression systems:
  • Escherichia coli BL21
  • Not provided