3im7

X-ray diffraction
2.21Å resolution

Crystal structure of mouse Ryanodine Receptor 2 N-terminal domain (1-217) disease mutant A77V

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ryanodine receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 217 amino acids
Theoretical weight: 24.2 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: E9Q401 (Residues: 1-217; Coverage: 4%)
Gene name: Ryr2
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: I41
Unit cell:
a: 112.211Å b: 112.211Å c: 36.773Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.223 0.275
Expression system: Escherichia coli