PDBe 3ikq

X-ray diffraction
2.25Å resolution

Crystal structure of alpha 1-2 mannobiose bound trimeric human lung surfactant protein D

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pulmonary surfactant-associated protein D Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 177 amino acids
Theoretical weight: 18.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P35247 (Residues: 199-375; Coverage: 50%)
Gene names: COLEC7, PSPD, SFTP4, SFTPD
Sequence domains:
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID13
Spacegroup: P21
Unit cell:
a: 55.91Å b: 108.78Å c: 56.08Å
α: 90° β: 90.19° γ: 90°
R-values:
R R work R free
0.202 0.202 0.239
Expression system: Escherichia coli BL21(DE3)