3gj9

X-ray diffraction
2.8Å resolution

crystal structure of TIP-1 in complex with c-terminal of Kir2.3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tax1-binding protein 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14907 (Residues: 1-124; Coverage: 100%)
Gene names: TAX1BP3, TIP1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Inward rectifier potassium channel 4 Chains: C, D
Molecule details ›
Chains: C, D
Length: 10 amino acids
Theoretical weight: 1.21 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P48050 (Residues: 436-445; Coverage: 2%)
Gene names: IRK3, KCNJ4

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P4322
Unit cell:
a: 86.457Å b: 86.457Å c: 101.517Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.247 0.247 0.27
Expression systems:
  • Escherichia coli
  • Not provided