X-ray diffraction
2.1Å resolution

Crystal structure of L3MBTL2-H4K20me1 complex


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Lethal(3)malignant brain tumor-like protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 456 amino acids
Theoretical weight: 52.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q969R5 (Residues: 170-625; Coverage: 65%)
Gene name: L3MBTL2
Sequence domains: mbt repeat
Structure domains: SH3 type barrels.

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 55.59Å b: 55.489Å c: 324.101Å
α: 90° β: 90° γ: 90°
R R work R free
0.203 0.199 0.268
Expression system: Escherichia coli