PDBe 3f1s

X-ray diffraction
2.3Å resolution

Crystal structure of Protein Z complexed with protein Z-dependent inhibitor

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein Z-dependent protease inhibitor Chain: A
Molecule details ›
Chain: A
Length: 385 amino acids
Theoretical weight: 44.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UK55 (Residues: 60-444; Coverage: 91%)
Gene names: SERPINA10, UNQ707/PRO1358, ZPI
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:
Vitamin K-dependent protein Z Chain: B
Molecule details ›
Chain: B
Length: 283 amino acids
Theoretical weight: 31.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P22891 (Residues: 125-400; Coverage: 73%)
Gene name: PROZ
Sequence domains: Trypsin
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 68.562Å b: 96.514Å c: 117.077Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.224 0.271
Expression system: Escherichia coli