› 3elm

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155288 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagenase 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 171 amino acids
Theoretical weight: 19.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P45452 (Residues: 104-274; Coverage: 38%)
Gene name: MMP13
Sequence domains: Matrixin
Structure domains: Collagenase (Catalytic Domain)

Ligands and Environments

3 bound ligands:
Ligand ZN 4 x ZN
Ligand CA 7 x CA
Ligand 24F 2 x 24F
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: C2
Unit cell:
a: 134.5Å b: 36.07Å c: 95.18Å
α: 90° β: 130.53° γ: 90°
R-values:
R R work R free
0.164 0.164 0.202
Expression system: Escherichia coli

Quick links

Citations

5 review citations

New molecular targets for the treatment of osteoarthritis.
Alcaraz et al. (2010)
4 more

5 mentions without citation

Molecular basis of lipid antigen presentation by CD1d and recognition by natural killer T cells.
Girardi et al. (2012)
4 more