3e9l

X-ray diffraction
1.95Å resolution

Crystal Structure of Human Prp8, Residues 1755-2016

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pre-mRNA-processing-splicing factor 8 Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 29.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6P2Q9 (Residues: 1760-2016; Coverage: 11%)
Gene names: PRPC8, PRPF8
Sequence domains: PRP8 domain IV core
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P3221
Unit cell:
a: 83.426Å b: 83.426Å c: 96.263Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.22 0.205 0.248
Expression system: Escherichia coli