X-ray diffraction
2.7Å resolution

Crystal structure of the human Fe65-PTB1 domain with bound phosphate (trigonal crystal form)

Source organism: Homo sapiens
Primary publication:
Crystal structure of the human Fe65-PTB1 domain.
J. Biol. Chem. 283 23113-20 (2008)
PMID: 18550529

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Amyloid-beta A4 precursor protein-binding family B member 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 148 amino acids
Theoretical weight: 16.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O00213 (Residues: 366-505; Coverage: 20%)
Gene names: APBB1, FE65, RIR
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: R3
Unit cell:
a: 146.04Å b: 146.04Å c: 78.294Å
α: 90° β: 90° γ: 120°
R R work R free
0.245 0.242 0.313
Expression system: Escherichia coli