3bua

X-ray diffraction
2.5Å resolution

Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero octamer
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Telomeric repeat-binding factor 2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 204 amino acids
Theoretical weight: 23.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15554 (Residues: 84-287; Coverage: 38%)
Gene names: TERF2, TRBF2, TRF2
Structure domains: Telomere repeat-binding factor, dimerisation domain
5' exonuclease Apollo Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 36 amino acids
Theoretical weight: 4.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H816 (Residues: 495-530; Coverage: 7%)
Gene names: DCLRE1B, SNM1B

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P3221
Unit cell:
a: 109.947Å b: 109.947Å c: 130.83Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.229 0.229 0.254
Expression system: Escherichia coli BL21(DE3)